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Article

The planar polarity gene strabismus regulates convergent extension movements in Xenopus.

The EMBO journal - 1 Mar 2002

Darken Rachel S, Scola Adriane M, Rakeman Andrew S, Das Gishnu, Mlodzik Marek, Wilson Paul A

Abstract excerpt

The signaling mechanisms that specify, guide and coordinate cell behavior during embryonic morphogenesis are poorly understood. We report that a Xenopus homolog of the Drosophila planar cell polarity gene strabismus (stbm) participates in the regulation of convergent extension, a critical morphogenetic process required for the elongation of dorsal structures in vertebrate embryos. Overexpression of Xstbm, which...

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Identifiers

PMID: 11867525
DOI: 10.1093/emboj/21.5.976
PMCID: PMC125882

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