Article
Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements.
Nature cell biology - 1 Aug 2002
Jessen Jason R, Topczewski Jacek, Bingham Stephanie, Sepich Diane S, Marlow Florence, Chandrasekhar Anand, Solnica-Krezel Lilianna
Abstract excerpt
Embryonic morphogenesis is driven by a suite of cell behaviours, including coordinated shape changes, cellular rearrangements and individual cell migrations, whose molecular determinants are largely unknown. In the zebrafish, Dani rerio, trilobite mutant embryos have defects in gastrulation movements and posterior migration of hindbrain neurons. Here, we have used positional cloning to demonstrate that trilobite...
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