Article
Neural tube closure requires Dishevelled-dependent convergent extension of the midline.
Development (Cambridge, England) - 1 Dec 2002
Wallingford John B, Harland Richard M
Abstract excerpt
In Xenopus, Dishevelled (Xdsh) signaling is required for both neural tube closure and neural convergent extension, but the connection between these two morphogenetic processes remains unclear. Indeed normal neurulation requires several different cell polarity decisions, any of which may require Xdsh signaling. In this paper we address two issues: (1) which aspects of normal neurulation require Xdsh function; and...
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