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Article

Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer.

Cancer research - 15 Feb 2002

Tan Duan-Jun, Bai Ren-Kui, Wong Lee-Jun C

Abstract excerpt

To investigate the role of mitochondrial DNA (mtDNA) in tumorigenesis, a temporal temperature gradient gel electrophoresis method was used to analyze the somatic mtDNA mutations in breast cancer. The entire mitochondrial genomes in 19 tumor samples and paired normal tissues from the same patients were amplified using 32 pairs of overlapping primers. DNA fragments showing different banding patterns between normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11861366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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