Article
Alleles and intron polymorphism of KIR3DL1 shown by combination of allele group-specific primers and sequencing.
Tissue antigens - 1 Dec 2008
Sun J Y, Oki A, Senitzer D
Abstract excerpt
Allelic polymorphism of killer immunoglobulin-like receptor (KIR) genes may affect receptor expression as well as function. We used a combination of allele group-specific primers and DNA sequencing techniques to verify our KIR genotyping primers in polymerase chain reaction and identified three KIR3DL1 alleles. By sequencing some introns of 3DL1 in 18 genomic DNA samples, we found that a 4-bp insert in intron 1...
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