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Article

Concurrent overexpression of Ets-1 and c-Met correlates with a phenotype of high cellular motility in human esophageal cancer.

International journal of cancer - 1 Mar 2002

Saeki Hiroshi, Oda Shinya, Kawaguchi Hidetoshi, Ohno Shinji, Kuwano Hiroyuki, Maehara Yoshihiko, Sugimachi Keizo

Abstract excerpt

Hepatocyte growth factor (HGF) stimulates cell motility as well as mitotic activity of cells. High concentrations of HGF or overexpression of its cellular receptor c-Met in cancer have been reported. We analyzed the expression status of c-Met immunohistochemically in 76 cases of human esophageal cancer. Overexpression of c-Met was noted at a considerably high frequency. Intriguingly, c-Met overexpression was...

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Source

Identifiers

PMID: 11857377
DOI: 10.1002/ijc.10163

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Concurrent overexpression of Ets-1 and c-Met correlates with a phenotype of high cellular motility in human esophageal cancer.PMID 11857377Read ↗

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