c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells.

doi:10.1074/jbc.273.50.33714

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cells.

The Journal of biological chemistry - 11 Dec 1998

Rahimi N, Hung W, Tremblay E, Saulnier R, Elliott B

Abstract excerpt

Overexpression and amplification of hepatocyte growth factor (HGF) receptor (Met) have been detected in many types of human cancers, suggesting a critical role for Met in growth and development of malignant cells. However, the molecular mechanism by which Met contributes to tumorigenesis is not w...

Topics

Animals
CSK Tyrosine-Protein Kinase
Cell Adhesion
Cell Division
Cell Movement
Hepatocyte Growth Factor
Mammary Neoplasms, Experimental
Mice
Phenotype
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-met
Tumor Cells, Cultured
src-Family Kinases

Source

Open in PubMed

Identifiers

PMID: 9837958
DOI: 10.1074/jbc.273.50.33714

Genes

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9837958-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics