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Article

Met overexpression confers HGF-dependent invasive phenotype to human thyroid carcinoma cells in vitro.

Journal of cellular physiology - 1 Sept 1999

de Luca A, Arena N, Sena L M, Medico E

Abstract excerpt

The proto-oncogene c-MET encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF), a pleiotropic cytokine controlling growth, survival, motility, invasive migration, and differentiation of epithelial cells. Like several other epithelial neoplasms, thyroid carcinomas have been found to overexpress c-MET at both the mRNA and protein level. The biological relevance of Met overexpression to thyroid...

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Source

Identifiers

PMID: 10430176
DOI: 10.1002/(SICI)1097-4652(199909)180:3<365::AID-JCP7>3.0.CO;2-B

Genes

HGF
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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