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Article

The receptor encoded by the human C‐<i>MET</i> oncogene is expressed in hepatocytes, epithelial cells and solid tumors

30 Sept 1991

Abstract excerpt

The human c-MET oncogene encodes a transmembrane tyrosine kinase (p190c-met) with structural and functional features of a growth-factor receptor. Monoclonal antibodies (MAbs) have been used to investigate the distribution of the c-Met protein in human normal and neoplastic tissues. By immunofluorescence microscopy homogeneous expression was detected in normal hepatocytes as well as in epithelial cells lining the...

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PMID: 1917129
DOI: 10.1002/ijc.2910490302

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