Article
A basolateral sorting motif in the MICA cytoplasmic tail.
Proceedings of the National Academy of Sciences of the United States of America - 5 Mar 2002
Suemizu Hiroshi, Radosavljevic Mirjana, Kimura Minoru, Sadahiro Sotaro, Yoshimura Shinichi, Bahram Seiamak, Inoko Hidetoshi
Abstract excerpt
The MHC class I chain-related MICA molecule is a stress-induced, highly polymorphic, epithelia-specific, membrane-bound glycoprotein interacting with the activating NK cell receptor NKG2D and/or gut-enriched Vdelta1-bearing gammadelta T cells. We have previously reported the presence of a MICA transmembrane-encoded short-tandem repeat harboring a peculiar allele, A5.1, characterized by a frame shift mutation...
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