Article
Condensin-dependent rDNA decatenation introduces a temporal pattern to chromosome segregation.
Current biology : CB - 22 Jul 2008
D'Ambrosio Claudio, Kelly Gavin, Shirahige Katsuhiko, Uhlmann Frank
Abstract excerpt
The chromosomal condensin complex gives metaphase chromosomes structural stability. In addition, condensin is required for sister-chromatid resolution during their segregation in anaphase [1-7]. How condensin promotes chromosome resolution is poorly understood. Chromosome segregation during anaphase also fails after inactivation of topoisomerase II (topo II), the enzyme that removes catenation between sister...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
