Article
Influence of p53 tumor suppressor protein on bias of DNA repair and apoptotic response in human cells.
Carcinogenesis - 1 May 1999
Wani M A, Zhu Q Z, El-Mahdy M, Wani A A
Abstract excerpt
A network of interacting cellular components is known to mediate the regulatory role of tumor suppressor protein p53 in genomic stability. DNA repair machinery is considered to be one of these vital cellular components. To investigate the modulatory function of p53 on the repair of DNA damage and related effects, we have studied the responses of human p53-wild-type (p53-WT), p53-mutant (p53-Mut) and...
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