Article
Lack of evidence for associations between plasma platelet-activating factor acetylhydrolase deficiency and schizophrenia.
Psychiatry research - 31 Jan 2002
Ohtsuki Tsuyuka, Watanabe Hideki, Toru Michio, Arinami Tadao
Abstract excerpt
Platelet-activating factor (PAF) is a potent phospholipid mediator that plays various roles in neuronal function and brain development. It is involved in NMDA receptor function. Release and degradation of PAF is controlled by intracellular and plasma PAF-acetylhydrolase (PAFAH). The plasma PAFAH gene (PLA2G7) is located on chromosome 6p. A previous study showed weak associations of the Ile198Thr and Val379Ala...
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