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Article

Platelet-activating factor acetylhydrolase gene polymorphism and its activity in Japanese patients with multiple sclerosis.

Journal of neuroimmunology - 1 May 2004

Osoegawa Manabu, Niino Masaaki, Ochi Hirofumi, Kikuchi Seiji, Murai Hiroyuki, Fukazawa Toshiyuki, Minohara Motozumi, Tashiro Kunio, Kira Jun-Ichi

Abstract excerpt

We evaluated the association of the plasma platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphism (G(994)-->T) and PAF-AH activity with susceptibility and severity of multiple sclerosis (MS) in Japanese. DNA was collected from 216 patients with clinically definite MS (65 opticospinal MS (OS-MS) and 151 conventional MS (C-MS)) and from 213 healthy controls. The missense mutation G(994)-->T that...

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PMID: 15081260
DOI: 10.1016/j.jneuroim.2004.01.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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