Lack of association between schizophrenia and the phospholipase-A(2) genes cPLA2 and sPLA2.

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Article

Lack of association between schizophrenia and the phospholipase-A(2) genes cPLA2 and sPLA2.

American journal of medical genetics - 8 Apr 2001

Frieboes R M, Moises H W, Gattaz W F, Yang L, Li T, Liu X, Vetter P, Macciardi F, Hwu H G, Henn F

Abstract excerpt

The well-established role of genetic factors in the etiology of schizophrenia together with reports of allelic association with cPLA2, a phospholipase-A(2) gene, a reported increase of phospholipase-A(2) activity, and the phospholipase-A(2) hypothesis of Horrobin et al. [1995: Med Hypotheses 45:605-613] strongly support cPLA2 (PLA2G4A) and sPLA2 (PLA2G1B) as candidate genes for schizophrenia. In search for...

Topics

Adolescent
Adult
Aged
Alleles
Asian People
Chi-Square Distribution
Female
Group II Phospholipases A2
Haplotypes
Humans
Male
Middle Aged
Parents
Phospholipases A
Polymorphism, Genetic

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Open in PubMed

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PMID: 11353443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Schizophrenia

Trinucleotide Repeats

White People