Article
Lack of association between schizophrenia and the phospholipase-A(2) genes cPLA2 and sPLA2.
American journal of medical genetics - 8 Apr 2001
Frieboes R M, Moises H W, Gattaz W F, Yang L, Li T, Liu X, Vetter P, Macciardi F, Hwu H G, Henn F
Abstract excerpt
The well-established role of genetic factors in the etiology of schizophrenia together with reports of allelic association with cPLA2, a phospholipase-A(2) gene, a reported increase of phospholipase-A(2) activity, and the phospholipase-A(2) hypothesis of Horrobin et al. [1995: Med Hypotheses 45:605-613] strongly support cPLA2 (PLA2G4A) and sPLA2 (PLA2G1B) as candidate genes for schizophrenia. In search for...
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