Article
Allelic association analysis of phospholipase A2 genes with schizophrenia.
Psychiatric genetics - 1 Sept 2004
Junqueira Ricardo, Cordeiro Quirino, Meira-Lima Ivanor, Gattaz Wagner Farid, Vallada Homero
Abstract excerpt
Several studies suggest increased activity of phospholipase A2 in schizophrenic patients. In the present study, variants of four genes coding for phospholipase A2 enzyme groups (sPLA2, cPLA2, iPLA2 and PAFAH) were analysed in a case-control sample using 240 schizophrenic patients and 312 healthy controls. No difference was observed on the allelic and genotypic distribution of cPLA2 and sPLA2 gene polymorphisms...
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