Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in PLA2G6 and PLA2G4C genes for calcium-independent phospholipase A2 do not contribute to attenuated niacin skin flush response in schizophrenia patients.

Prostaglandins, leukotrienes, and essential fatty acids - 1 Sept 2015

Nadalin S, Radović I, Buretić-Tomljanović A

Abstract excerpt

We hypothesized that attenuated niacin skin flushing in schizophrenia patients might be associated with polymorphic variants in PLA2G6 and PLA2G4C genes (rs4375 and rs1549637 variations) which encode calcium-independent phospholipase A2 beta (iPLA2β) and cytosolic phospholipase A2 gamma (cPLA2γ) enzymes. The iPLA2β and cPLA2γ may play an important role in niacin-mediated signaling; in addition to their major role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Croatia
Share to Flushing
Share to Group VI Phospholipases A2
Share to Niacin
Share to Polymorphism, Single Nucleotide
Share to Schizophrenia

Source

Identifiers

PMID: 26160611
DOI: 10.1016/j.plefa.2015.06.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in PLA2G6 and PLA2G4C genes for calcium-independent phospholipase A2 do not contribute to attenuated niacin skin flush response in schizophrenia patients.PMID 26160611Read ↗

The impact of PLA2G4A and PTGS2 gene polymorphisms, and red blood cell PUFAs deficit on niacin skin flush response in schizophrenia patients.Semantic proximity Read ↗

Niacin skin flush test: a research tool for studying schizophrenia.Semantic proximity Read ↗

Impaired Flush Response to Niacin Skin Patch Among Schizophrenia Patients and Their Nonpsychotic Relatives: The Effect of Genetic LoadingSemantic proximity Read ↗

A genome-wide quantitative linkage scan of niacin skin flush response in families with schizophrenia.Semantic proximity Read ↗

Endophenotype properties of niacin sensitivity as marker of impaired prostaglandin signalling in schizophrenia.Semantic proximity Read ↗

Familial aggregation in skin flush response to niacin patch among schizophrenic patients and their nonpsychotic relatives.Semantic proximity Read ↗

Blunted niacin skin flushing response in violent offenders with schizophrenia: A potential auxiliary diagnostic biomarkerSemantic proximity Read ↗

Causal associations between niacin bluntness and schizophrenia: a GWAS and Mendelian randomization studySemantic proximity Read ↗

Association of a long-chain fatty acid-CoA ligase 4 gene polymorphism with depression and with enhanced niacin-induced dermal erythema.Semantic proximity Read ↗

Altered HCAR3 expression may underlying the blunted niacin responses of the psychiatric disorders and the risk of schizophrenia.Semantic proximity Read ↗

Family-based and case-control studies reveal no association of lipocalin-type prostaglandin D2 synthase with schizophrenia.Semantic proximity Read ↗

Unraveling the causative connection between urticaria, inflammatory cytokines, and mental disorders: Perspectives from genetic evidence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.