Article
Systematic screening of the LDL-PLA2 gene for polymorphic variants and case-control analysis in schizophrenia.
Biochemical and biophysical research communications - 29 Dec 1997
Bell R, Collier D A, Rice S Q, Roberts G W, MacPhee C H, Kerwin R W, Price J, Gloger I S
Abstract excerpt
Systematic scans of the genome using microsatellite markers have identified chromosome 6p21.1 as a putative locus for schizophrenia in multiply affected families. There is also evidence from a series of studies for a role of abnormal phospholipid metabolism in schizophrenia. In light of these fin...
Topics
- Alleles
- Amino Acid Substitution
- Case-Control Studies
- Gene Frequency
- Genetic Testing
- Humans
- Lipoproteins, LDL
- Phospholipases A
- Phospholipases A2
- Polymorphism, Genetic
- Polymorphism, Single-Stranded Conformational
- Schizophrenia