Article
No association between the K variant of the butyrylcholinesterase gene and pathologically confirmed Alzheimer's disease.
Human molecular genetics - 1 May 1998
Singleton A B, Smith G, Gibson A M, Woodward R, Perry R H, Ince P G, Edwardson J A, Morris C M
Abstract excerpt
The polymorphic K variant of the butyrylcholinesterase ( BCHE-K ) gene recently has been demonstrated to have an elevated frequency in Alzheimer's disease (AD) patients carrying the epsilon4 allele of the apolipoprotein (APO E) gene when compared with a control population. We therefore genotyped a large series of pathologically confirmed AD patients and controls to confirm this association. We found no change in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.