Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.

Journal of medical genetics - 1 Dec 1998

Kehoe P G, Williams H, Holmans P, Wilcock G, Cairns N J, Neal J, Owen M J

Abstract excerpt

Previous work has shown an association between the K variant of the butyrylcholinesterase (BCHE) gene and Alzheimer's disease (AD) in patients carrying the epsilon4 allele of ApoE. We attempted to replicate this finding in 181 UK white AD cases and 71 controls. No difference was found in BCHE-K genotypes (p=0.75) or alleles (p=0.70) between patients and controls. Moreover, despite a significant excess of ApoE...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Apolipoproteins E

Share to Disease Susceptibility

Share to Genetic Variation

Share to Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 9863603
DOI: 10.1136/jmg.35.12.1034
PMCID: PMC1051518

Genes

BCHE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.PMID 9863603Read ↗

Butyrylcholinesterase K variant is genetically associated with late onset Alzheimer's disease in Northern Ireland.Semantic proximity Read ↗

No association between the K variant of the butyrylcholinesterase gene and pathologically confirmed Alzheimer's disease.Semantic proximity Read ↗

Butyrylcholinesterase K variant and Alzheimer's disease risk: a meta-analysis.Semantic proximity Read ↗

Butyrycholinesterase K variant and Alzheimer's disease.Semantic proximity Read ↗

The butyrylcholinesterase K variant is a protective factor for sporadic Alzheimer's disease in women.Semantic proximity Read ↗

Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer's disease patients.Semantic proximity Read ↗

No association between butyrylcholinesterase K-variant and Alzheimer disease in Chinese.Semantic proximity Read ↗

The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations.Semantic proximity Read ↗

Age-dependent association between butyrylcholinesterase K-variant and Alzheimer disease-related neuropathology in human brains.Semantic proximity Read ↗

Analysis of association between butyrylcholinesterase K variant and apolipoprotein E genotypes in Alzheimer's disease.Semantic proximity Read ↗

Homozygosity for the K variant of BCHE gene increases the risk for development of neurofibrillary pathology but not amyloid deposits at young ages.Semantic proximity Read ↗

Butyrylcholinesterase K variant and cerebral amyloid angiopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.