The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.

doi:10.1136/jmg.35.12.1034

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Article

The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.

Journal of medical genetics - 1 Dec 1998

Kehoe P G, Williams H, Holmans P, Wilcock G, Cairns N J, Neal J, Owen M J

Abstract excerpt

Previous work has shown an association between the K variant of the butyrylcholinesterase (BCHE) gene and Alzheimer's disease (AD) in patients carrying the epsilon4 allele of ApoE. We attempted to replicate this finding in 181 UK white AD cases and 71 controls. No difference was found in BCHE-K g...

Topics

Aged
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Butyrylcholinesterase
Disease Susceptibility
Female
Genetic Variation
Genotype
Humans
Male
Middle Aged

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