Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aberrant p53 Expression Correlates With Expression of Vascular Endothelial Growth Factor mRNA and Interleukin-8 mRNA and Neoangiogenesis in Non-Small-Cell Lung Cancer

15 Feb 2002

Abstract excerpt

PURPOSE: To evaluate interactions between expressions of tumor suppressor gene p53 and angiogenic factors vascular endothelial cell growth factor (VEGF) and interleukin-8 (IL-8) and their effect on tumor angiogenesis and patient prognosis in non--small-cell lung cancer (NSCLC). PATIENTS AND METHODS: p53, VEGF, IL-8, and the microvessel endothelium were immunostained, and VEGF and IL-8 mRNA expression were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Caveolin-1 and cellular processes
Share to Chemokine receptors and signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11844810
DOI: 10.1200/jco.20.4.900

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aberrant p53 Expression Correlates With Expression of Vascular Endothelial Growth Factor mRNA and Interleukin-8 mRNA and Neoangiogenesis in Non-Small-Cell Lung CancerPMID 11844810Read ↗

Interleukin-8 in non-small cell lung carcinoma: relation with angiogenic pattern and p53 alterations.Semantic proximity Read ↗

VEGF-A Expression Correlates with TP53 Mutations in Non-Small Cell Lung Cancer: Implications for Antiangiogenesis Therapy.Semantic proximity Read ↗

The K-ras gene regulates vascular endothelial growth factor gene expression in non-small cell lung cancers.Semantic proximity Read ↗

[Clinical significance of mutant p53 protein expression in lung adenocarcinoma].Semantic proximity Read ↗

Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer.Semantic proximity Read ↗

Mutations in exon 7 and 8 of p53 as poor prognostic factors in patients with non-small cell lung cancer.Semantic proximity Read ↗

Alternative Splicing Variant of Kallikrein-Related Peptidase 8 as an Independent Predictor of Unfavorable Prognosis in Lung CancerSemantic proximity Read ↗

Clinicopathological and prognostic significance of interleukin-8 expression and its relationship to KRAS mutation in lung adenocarcinoma.Semantic proximity Read ↗

Thrombospondins I and II messenger RNA expression in lung carcinoma: relationship with p53 alterations, angiogenic growth factors, and vascular density.Semantic proximity Read ↗

Tissue factor expression in non-small cell lung cancer: relationship with vascular endothelial growth factor expression, microvascular density, and K-ras mutation.Semantic proximity Read ↗

MDM2 mRNA expression is a favorable prognostic factor in non-small-cell lung cancerSemantic proximity Read ↗

Tumor angiogenesis and p53 mutations: prognosis in head and neck cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.