Article
The K-ras gene regulates vascular endothelial growth factor gene expression in non-small cell lung cancers.
International journal of oncology - 1 Mar 2000
Konishi T, Huang C L, Adachi M, Taki T, Inufusa H, Kodama K, Kohno N, Miyake M
Abstract excerpt
Tumor angiogenesis is an essential step for tumor cell growth, progression and metastasis. Vascular endothelial growth factor (VEGF) is mitogen specific for endothelial cells, and therefore is believed to play a key role in tumor angiogenesis. However, the mechanisms underlying the regulation of...
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