Article
Interleukin-8 in non-small cell lung carcinoma: relation with angiogenic pattern and p53 alterations.
Lung cancer (Amsterdam, Netherlands) - 1 Dec 2005
Boldrini Laura, Gisfredi Silvia, Ursino Silvia, Lucchi Marco, Mussi Alfredo, Basolo Fulvio, Pingitore Raffaele, Fontanini Gabriella
Abstract excerpt
Progression of solid tumors, including NSCLC, is associated with increase in MVC (microvessel count), as a measure of tumor angiogenesis resulting from an imbalance between angiogenic factors and inhibitors. However, since tumor angiogenesis is a multi-step process under the control of various molecules, the mechanism of angiogenesis has not been fully clarified. Interleukin (IL)-8 has been shown to have a...
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