Article
Tumor angiogenesis and p53 mutations: prognosis in head and neck cancer.
Archives of otolaryngology--head & neck surgery - 1 Jan 1998
Hegde P U, Brenski A C, Caldarelli D D, Hutchinson J, Panje W R, Wood N B, Leurgans S, Preisler H D, Taylor S G, Caldarelli L, Coon J S
Abstract excerpt
OBJECTIVES: To assess how p53 gene mutations and microvessel density (MVD) may be used as prognostic markers for the study and management of head and neck squamous cell carcinomas and to investigate putative associations between p53 gene mutations and MVD and the relationship of these factors to tumor response to radiotherapy and/or chemotherapy at 6 weeks. PATIENTS AND DESIGN: Thirty-nine patients with squamous...
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