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Article

Frequent CpG island methylation in serrated adenomas of the colorectum.

The American journal of pathology - 1 Mar 2003

Park Seun-Ja, Rashid Asif, Lee Jae-Hyuk, Kim Sang Geol, Hamilton Stanley R, Wu Tsung-Teh

Abstract excerpt

Serrated adenomas are characterized by a saw-toothed growth pattern with epithelial dysplasia (intraepithelial neoplasia). The CpG island methylator phenotype (CIMP) is a recently described mechanism for tumorigenesis in colorectal carcinomas and adenomas characterized by methylation of multiple CpG islands. The role of these epigenetic alterations in the pathogenesis of serrated adenomas is not clear. We...

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Identifiers

PMID: 12598316
DOI: 10.1016/S0002-9440(10)63878-3
PMCID: PMC1868094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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