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Article

The CIMP Phenotype in<i>BRAF</i>Mutant Serrated Polyps from a Prospective Colonoscopy Patient Cohort

1 Jan 2014

Abstract excerpt

Colorectal cancers arising via the serrated pathway are often associated with BRAF V600E mutation, CpG island methylator phenotype (CIMP), and microsatellite instability. Previous studies have shown a strong association between BRAF V600E mutation and serrated polyps. This study aims to evaluate CIMP status of all the serrated polyp subtypes and its association with functionally important genes such as MLH1, p16,...

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Identifiers

PMID: 24812557
DOI: 10.1155/2014/374926

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