Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

p53 mutation pattern and expression of c-erbB2 and c-met in gastric cancer: relation to histological subtypes, Helicobacter pylori infection, and prognosis.

Digestive diseases and sciences - 1 Jan 2002

Kubicka Stefan, Claas Christiane, Staab Sven, Kühnel Florian, Zender Lars, Trautwein Christian, Wagner Siegfried, Rudolph Karl Lenhard, Manns Michael

Abstract excerpt

The molecular mechanisms of Helicobacter pylori associated tumor development are poorly understood. The spectra of genetic alterations in neoplasms may provide clues to the molecular carcinogenesis of a tumor and may be relevant for the prognosis of the patients. We investigated the p53 mutation pattern and the protein expression of p53, c-erbB2, and c-met in 42 gastric cancers and correlated these alterations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, erbB-2
Share to Genes, p53

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Lymphatic Metastasis

Share to Mutation

Share to Prognosis

Share to Stomach Neoplasms

Source

Identifiers

PMID: 11837710
DOI: 10.1023/a:1013275706401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

p53 mutation pattern and expression of c-erbB2 and c-met in gastric cancer: relation to histological subtypes, Helicobacter pylori infection, and prognosis.PMID 11837710Read ↗

Relationship of p53 and c-erbB-2 expression to histopathological features, Helicobacter pylori infection and prognosis in gastric cancer.Semantic proximity Read ↗

TP53 and gastric carcinoma: a review.Semantic proximity Read ↗

A study on the effect of Helicobacter pylori infection on p53 expression in gastric cancer and gastritis tissues.Semantic proximity Read ↗

Prediction of TP53 mutations by p53 immunohistochemistry and their prognostic significance in gastric cancerSemantic proximity Read ↗

Redefining aberrant P53 expression of gastric cancer and its distinct clinical significance among molecular-histologic subtypes.Semantic proximity Read ↗

Comparable genetic alteration profiles between gastric cancers with current and past Helicobacter pylori infection.Semantic proximity Read ↗

The prognostic significance of p21 and Her-2 gene expression and mutation/polymorphism in patients with gastric adenocarcinoma.Semantic proximity Read ↗

Molecular mechanisms involved in the pathogenesis of gastric carcinoma: interactions between genetic alterations, cellular phenotype and cancer histotype.Semantic proximity Read ↗

Helicobacter pylori bacteria alter the p53 stress response via Erk-HDM2 pathwaySemantic proximity Read ↗

Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.Semantic proximity Read ↗

Accumulation of somatic mutations in TP53 in gastric epithelium with Helicobacter pylori infection.Semantic proximity Read ↗

Correlation between Patterns of Mdm2 SNIP 309 and Histopathological Severity of Helicobacter pylori Associated Gastritis in Thailand.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.