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Article

Comparable genetic alteration profiles between gastric cancers with current and past Helicobacter pylori infection.

Scientific reports - 6 Dec 2021

Tsuyuki Sho, Takeshima Hideyuki, Sekine Shigeki, Yamagata Yukinori, Ando Takayuki, Yamashita Satoshi, Maeda Shin, Yoshikawa Takaki, Ushijima Toshikazu

Abstract excerpt

Gastric cancers can develop even after Helicobacter pylori (H. pylori) eradication in 0.2-2.9% cases per year. Since H. pylori is reported to directly activate or inactivate cancer-related pathways, molecular profiles of gastric cancers with current and past H. pylori infection may be different. Here, we aimed to analyze whether profiles of point mutation and gene amplification are different between the two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34873204
DOI: 10.1038/s41598-021-02761-7
PMCID: PMC8648804

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