Article
A study on the effect of Helicobacter pylori infection on p53 expression in gastric cancer and gastritis tissues.
Journal of infection in developing countries - 16 Sept 2013
Salih Barik A, Gucin Zuhal, Bayyurt Nizamettin
Abstract excerpt
INTRODUCTION: Helicobacter pylori cause damage to gastric epithelial cells and alterations in the p53 gene that lead to cancer development. This study aimed to determine the correlation of p53 expression with H. pylori using immunohistochemistry, RFLP-PCR, and histopathology. METHODOLOGY: Gastric biopsy samples from gastric cancer (GC) (n = 54) and gastritis (n = 31) patients were examined for histopathological...
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