Article
The prognostic significance of p21 and Her-2 gene expression and mutation/polymorphism in patients with gastric adenocarcinoma.
Medical oncology (Northwood, London, England) - 1 Mar 2013
Ozen Alaattin, Kocak Zafer, Sipahi Tammam, Oz-Puyan Fulya, Cakina Suat, Saynak Mert, Ibis Cem, Karagol Hakan
Abstract excerpt
Analyses of gene expression status and genetic polymorphisms are methods to identify novel histopathological prognostic factors. In patients with gastric cancer, some cell cycle regulators p53, p21, p27 and Her-2 oncogene have been proposed as prognostic factors. We aimed to investigate the expression and mutation/polymorphism of p21 and Her-2 and also relationship between that genes status and histopathological...
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