Article
Redefining aberrant P53 expression of gastric cancer and its distinct clinical significance among molecular-histologic subtypes.
Asian journal of surgery - 1 Nov 2024
Huang Shih-Chiang, Chang Ian Yi-Feng, Chen Tse-Ching, Lin Hsiao-Ching, Tsai Chun-Yi, Hsu Jun-Te, Yeh Chun-Nan, Chang Shih-Cheng, Yeh Ta-Sen
Abstract excerpt
BACKGROUND: Numerous studies have demonstrated a correlation between p53 overexpression and diminished survival in gastric cancer patients. However, conflicting findings exist, and we hypothesize that these discrepancies arise from the cancer's complexity and heterogeneity, coupled with a lack of consensus on aberrant p53 expression. METHODS: We enrolled a cohort of 187 patients with surgically resected gastric...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
