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Article

Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.

World journal of gastroenterology - 1 Jan 2003

Lan Jing, Xiong Yong-Yan, Lin Yi-Xian, Wang Bi-Cheng, Gong Ling-Ling, Xu Hui-Sen, Guo Guang-Song

Abstract excerpt

AIM: To investigate the relationship between Helicobacter pylori (H.pylori) infection and the expressions of the p53, Rb, c-myc, bcl-2 and hTERT mRNA in a series of diseases from chronic gastritis (CG), intestinal metaplasia type I or II(IMI-II), intestinal metaplasia type III (IMIII), mild or modest dysplasia (DysI-II), severe dysplasia (DysIII) to gastric cancer(GC) and to elucidate the mechanism of gastric...

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Identifiers

PMID: 12508351
DOI: 10.3748/wjg.v9.i1.54
PMCID: PMC4728249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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