Article
[Detection of K-ras gene mutations in DNA extracted from the plasma of patients with pancreatic cancer].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 1 Oct 2000
Feng D, Han T, Jiang Y, Yuan Z, Wang X, Jiang Z, Zhang S
Abstract excerpt
OBJECTIVES: To detect mutations of the K-ras codon 12 in DNA extracted from the plasma of patients with pancreatic cancer, and to explore the possibility of using this method in early diagnosis of pancreatic cancer. METHODS: Plasma DNA was isolated from the blood of 22 patients with pancreatic cancer and from 20 normal controls. K-ras codon 12 mutations were detected by mutant enriched polymerase chain...
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