Article
Detection of K-ras mutations in the plasma DNA of pancreatic cancer patients.
Journal of gastroenterology - 1 Jan 2004
Uemura Takanori, Hibi Kenji, Kaneko Tetsuya, Takeda Shin, Inoue Soichiro, Okochi Osamu, Nagasaka Tetsuro, Nakao Akimasa
Abstract excerpt
BACKGROUND: In pancreatic cancers, K-ras mutations have been found frequently (80%-100%), and they could be a good marker to detect tumor DNA in the plasma. Several studies have indicated that polymerase chain reaction/restriction fragment length polymorphism (PCR/RFLP) analysis of K-ras mutation...
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