Article
[Significance of detection of K-ras gene mutations and CA19-9 in serum for diagnosis of pancreatic carcinoma].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Mar 2003
Zhang Yi, Ji Shu-Rong, Feng Dian-Xu, Ji Jun, Han Tian-Quan
Abstract excerpt
BACKGROUND & OBJECTIVE: The early diagnosis of pancreatic carcinoma is difficult. The serum tumor markers such as CA19-9 have a relatively high sensitivity but with low specificity. The oncogene K-ras is frequently mutated in pancreatic carcinoma and with high specificity. The aim of this study was to assess the feasibility of detection of K-ras mutation combined with serum content of CA19-9 as an approach for...
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