Article
Detection of K-ras gene mutation by liquid biopsy in patients with pancreatic cancer.
Cancer - 1 Jul 2015
Kinugasa Hideaki, Nouso Kazuhiro, Miyahara Koji, Morimoto Yuki, Dohi Chihiro, Tsutsumi Koichiro, Kato Hironari, Matsubara Takehiro, Okada Hiroyuki, Yamamoto Kazuhide
Abstract excerpt
BACKGROUND: Cell-free circulating tumor DNA (ctDNA) in serum has been considered to be a useful candidate for noninvasive cancer diagnosis. The current study was designed to estimate the clinical usefulness of genetic analysis for ctDNA by digital polymerase chain reaction in patients with pancreatic cancer. METHODS: The authors compared K-ras mutations detected in endoscopic ultrasound-guided fine-needle...
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