Article
K-ras mutational status predicts poor prognosis in unresectable pancreatic cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Jul 2010
Chen H, Tu H, Meng Z Q, Chen Z, Wang P, Liu L M
Abstract excerpt
OBJECTIVE: To determine the prognostic value of K-ras mutations in plasma DNA of unresectable pancreatic cancer patients. METHODS: Blood samples were collected from 91 patients with unresectable pancreatic cancer prior to treatment. K-ras gene was amplified from the circulating plasma DNA. Mutations were detected by direct sequencing. The relationship between the types of K-ras gene and prognosis of unresectable...
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