Article
Differential association of polymorphisms in the TNFalpha region with psoriatic arthritis but not psoriasis.
Annals of the rheumatic diseases - 1 Mar 2002
Höhler T, Grossmann S, Stradmann-Bellinghausen B, Kaluza W, Reuss E, de Vlam K, Veys E, Märker-Hermann E
Abstract excerpt
OBJECTIVE: To investigate the potential association of tumour necrosis factor alpha (TNFalpha) microsatellite and promoter alleles with psoriatic arthritis (PsA). METHODS: DNA from 89 white patients with PsA, 65 patients with psoriasis, and 99 healthy white controls was investigated for two TNFalpha promoter (-238 and -308) and three microsatellite polymorphisms (TNFa, c, and d). Patients had previously been...
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