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Article

Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severity.

Arthritis and rheumatism - 1 May 2003

Balding Joanna, Kane David, Livingstone Wendy, Mynett-Johnson Lesley, Bresnihan Barry, Smith Owen, FitzGerald Oliver

Abstract excerpt

OBJECTIVE: To determine whether functional cytokine gene polymorphisms influence disease susceptibility and phenotype in patients with psoriatic arthritis (PsA). METHODS: DNA was obtained from 147 PsA patients and 389 controls. Seven functional proinflammatory (interleukin-1beta [IL-1beta] +3953, IL-6 -174, tumor necrosis factor alpha [TNFalpha] -308, TNFbeta +252) and antiinflammatory (IL-10 -1082, IL-10 -592,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12746914
DOI: 10.1002/art.10935

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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