Article

308G/A and 238G/A polymorphisms in the TNF-α gene may not contribute to the risk of arthritis among Turkish psoriatic patients

2016-04-05

Abstract excerpt

Tumor necrosis factor-alpha (TNF-α) is an important proinflammatory cytokine playing a key role in the pathogenesis of psoriasis (Ps) and psoriatic arthritis (PsA). TNFα gene promoter region single nucleotide polymorphisms (SNPs) affect the clinical course, severity and the response to the treatment. To find out whether TNF-α-238G/A and -308G/A promoter polymorphism in Ps patients increases arthritis risk. The stu...

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Literature Corpus work: dbd69df4-64fd-590b-a208-c6cb3cf0c9a3
DOI: 10.1016/j.ejr.2016.02.005

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