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Article

Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

Oncogene - 17 Jan 2002

Saintigny Yannick, Lopez Bernard S

Abstract excerpt

Cell cycle control, faithful DNA replication, repair and recombination are associated in a network of pathways controlling genome maintenance. In mammalian cells, inhibition of replication produces DNA breaks and induces RAD51-dependent recombination, in a late step. Here we examine whether the status of p53 affects this process in mouse L-cells containing a recombination substrate. We show that expression of the...

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Source

Identifiers

PMID: 11821962
DOI: 10.1038/sj.onc.1205040

Genes

RAD51

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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