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Article

Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53.

Oncogene - 14 Sept 2000

Süsse S, Janz C, Janus F, Deppert W, Wiesmüller L

Abstract excerpt

Our previous work (Dudenhöffer et al., 1999) unveiled a link between the capacity of p53 to regulate homologous recombination processes and to specifically bind to heteroduplex junction DNAs. Here, we show that p53 participates in ternary complex formation after preassembly of nucleoproteins, consisting of the human recombinase hRad51 and junction DNA. The cancer-related mutant p53(273H), which is defective in...

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Share to Base Sequence
Share to DNA-Binding Proteins
Share to DNA Nucleotidyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Rad51 Recombinase

Share to Recombination, Genetic

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Source

Identifiers

PMID: 11002423
DOI: 10.1038/sj.onc.1203809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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