Article

Rad51 is a druggable target that sustains replication fork progression upon DNA replication stress

2022-03-26

Abstract excerpt

Solving the problems that replication forks encounter when synthesizing DNA is essential to prevent genomic instability. Besides their role in DNA repair in the G2 phase, several homologous recombination proteins, specifically Rad51, have prominent roles in the S phase. Using different cellular models, Rad51 has been shown not only to be present at ongoing and arrested replication forks but also to be involved in...

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Identifiers and source

Literature Corpus work: 929f7d77-0bb8-580c-82e0-ee2e162d9883
DOI: 10.1101/2022.03.25.485778

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