Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic dissection of granulomatous enterocolitis and arthritis in the intramural peptidoglycan-polysaccharide-treated rat model of IBD.

Inflammatory bowel diseases - 1 Dec 2009

Bleich A, Hopf S, Hedrich H J, van Lith H A, Li F, Balfour Sartor R, Mähler M

Abstract excerpt

BACKGROUND: Inflammatory arthropathies are common extraintestinal manifestations of inflammatory bowel diseases (IBD). As genetic susceptibility plays an important role in the etiology of IBD, we questioned how granulomatous enterocolitis and arthritis are genetically controlled in an experimental animal model displaying both conditions. METHODS: Chronic intestinal and systemic inflammation was induced by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Granulomatous Disease, Chronic

Share to Inflammatory Bowel Diseases

Share to Peptidoglycan

Share to Quantitative Trait Loci

Share to Rats, Inbred F344

Share to Rats, Inbred Lew

Source

Open in PubMed Open full text

Identifiers

PMID: 19526527
DOI: 10.1002/ibd.21018
PMCID: PMC2889022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic dissection of granulomatous enterocolitis and arthritis in the intramural peptidoglycan-polysaccharide-treated rat model of IBD.PMID 19526527Read ↗

Genetic links between the acute-phase response and arthritis development in rats.Semantic proximity Read ↗

Experimental murine colitis is regulated by two genetic loci, including one on chromosome 11 that regulates IL-12 responses.Semantic proximity Read ↗

Gut microbiota and blood biomarkers in IBD-Related arthritis: insights from mendelian randomization.Semantic proximity Read ↗

A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis.Semantic proximity Read ↗

Genetic analysis of collagen-induced arthritis in rats: a polygenic model for rheumatoid arthritis predicts a common framework of cross-species inflammatory/autoimmune disease loci.Semantic proximity Read ↗

Mapping colitis susceptibility in mouse models: distal chromosome 3 contains major loci related to Cdcs1.Semantic proximity Read ↗

High resolution mapping of an arthritis susceptibility locus on rat chromosome 4, and characterization of regulated phenotypes.Semantic proximity Read ↗

Translocation of intestinal peptidoglycan moieties modulates the early stages of arthritis.Semantic proximity Read ↗

Sex effect on clinical and immunologic quantitative trait loci in a murine model of rheumatoid arthritis.Semantic proximity Read ↗

The intimate relationship between gut and joint in spondyloarthropathies.Semantic proximity Read ↗

QTL Mapping of Intestinal Neutrophil Variation in Threespine Stickleback Reveals Possible Gene Targets Connecting Intestinal Inflammation and Systemic Health.Semantic proximity Read ↗

Enteropathic spondyloarthropathy: a common genetic background with inflammatory bowel disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.