Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A-tract DNA disfavours triplex formation.

Journal of molecular biology - 25 Jan 2002

Sandström Karin, Wärmländer Sebastian, Gräslund Astrid, Leijon Mikael

Abstract excerpt

Optimisation of DNA triplex stability is of fundamental importance in the anti-gene strategy. In the present work, thermal denaturation studies by UV-spectrophotometry and structural and dynamical characterizations by NMR spectroscopy have been used systematically to investigate the effects on triplex stability of isolated insertions of different base triplets into an otherwise homogeneous 15-mer dT x dA-dT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Sodium Chloride
Share to Base Composition
Share to Base Pairing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Magnetic Resonance Spectroscopy

Share to Nucleic Acid Conformation

Share to Nucleic Acid Denaturation

Share to Poly A

Share to Spectrophotometry, Ultraviolet

Source

Identifiers

PMID: 11812143
DOI: 10.1006/jmbi.2001.5249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A-tract DNA disfavours triplex formation.PMID 11812143Read ↗

DNA-triplex stabilizing properties of 8-aminoguanine.Semantic proximity Read ↗

Thermodynamic Stability of DNA Duplexes Comprising the Simplest T → dU Substitutions.Semantic proximity Read ↗

G-quadruplexes incorporating modified constituents: a review.Semantic proximity Read ↗

Formation of intramolecular triplex in homopurine-homopyrimidine mirror repeats with point substitutions.Semantic proximity Read ↗

Sequence context effect on strand slippage in natural DNA primer-templates.Semantic proximity Read ↗

Diffusion-ordered nuclear magnetic resonance spectroscopy for analysis of DNA secondary structural elements.Semantic proximity Read ↗

Antiproliferative Effects of the Aptamer d(GGGT)4 and Its Analogues with an Abasic-Site Mimic Loop on Different Cancer CellsSemantic proximity Read ↗

O6-methylguanine and A.C and G.T mismatches cause asymmetric structural defects in DNA that are affected by DNA sequence.Semantic proximity Read ↗

Sequence specificity in triple-helix formation: experimental and theoretical studies of the effect of mismatches on triplex stability.Semantic proximity Read ↗

The effect of amino groups on the stability of DNA duplexes and triplexes based on purines derived from inosine.Semantic proximity Read ↗

A further contribution to the extreme variability of quadruplex structures from oligodeoxyribonucleotides containing inversion of polarity sites in the G-tract.Semantic proximity Read ↗

Sequence variant (CTAGGG)n in the human telomere favors a G-quadruplex structure containing a G.C.G.C tetrad.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.