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Article

Formation of intramolecular triplex in homopurine-homopyrimidine mirror repeats with point substitutions.

Nucleic acids research - 25 Nov 1990

Belotserkovskii B P, Veselkov A G, Filippov S A, Dobrynin V N, Mirkin S M, Frank-Kamenetskii M D

Abstract excerpt

We have used two-dimensional gel electrophoresis to study the structural transition to the triplex H form of sequences 5'-AAGGGAGAAXGGGGTATAGGGGYAAGAGGGAA-3' where X and Y are any DNA bases. The transition was observed at acid pH under superhelical stress. For X = Y = A or X = Y = G the sequences corresponded to homopurine-homopyrimidine mirror repeats (H-palindrome) which are known to adopt the H form under acid...

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Identifiers

PMID: 2251122
DOI: 10.1093/nar/18.22.6621
PMCID: PMC332619

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Source receipt: pubmed, retrieved 7 Sept 2026.

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