Article
The loss of Drosophila APG4/AUT2 function modifies the phenotypes of cut and Notch signaling pathway mutants.
Molecular genetics and genomics : MGG - 1 Dec 2001
Thumm M, Kadowaki T
Abstract excerpt
A P-element line ( P0997) of Drosophila melanogaster in which the P element disrupts the Drosophila homolog of the Saccharomyces cerevisiae gene APG4/AUT2 was identified during the course of screening for cut ( ct) modifiers. The yeast gene APG4/AUT2 encodes a cysteine endoprotease directed against Apg8/Aut7 and is necessary for autophagy. The P0997 mutation enhances the wing margin loss associated with ct...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
