Article
A genomic screen identifies AUT8 as a novel gene essential for autophagy in the yeast Saccharomyces cerevisiae.
Gene - 22 Aug 2001
Barth H, Thumm M
Abstract excerpt
Autophagy is a starvation-induced transport pathway delivering parts of the cytosol into the lysosome (vacuole) for degradation. Autophagy significantly differs from other transport pathways by using double membrane layered transport intermediates. Based on the identification of autophagy genes in Saccharomyces cerevisiae, which served as a pacemaker for higher cells, our mechanistic knowledge of autophagy...
Topics
- Amino Acid Sequence
- Aminopeptidases
- Autophagy
- Enzyme Precursors
- Eosine I Bluish
- Fungal Proteins
- Genome, Fungal
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins