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Article

The activity of yeast Apn2 AP endonuclease at uracil-derived AP sites is dependent on the major carbon source.

Current genetics - 1 Apr 2021

Stokdyk Kasey, Berroyer Alexandra, Grami Zacharia A, Kim Nayun

Abstract excerpt

Yeast Apn2 is an AP endonuclease and DNA 3'-diesterase that belongs to the Exo III family with homology to the E. coli exonuclease III, Schizosaccharomyces pombe eth1, and human AP endonucleases APEX1 and APEX2. In the absence of Apn1, the major AP endonuclease in yeast, Apn2 can cleave the DNA backbone at an AP lesion initiating the base excision repair pathway. To study the role and relative contribution of...

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Identifiers

PMID: 33386486
DOI: 10.1007/s00294-020-01141-4
PMCID: PMC8035244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The activity of yeast Apn2 AP endonuclease at uracil-derived AP sites is dependent on the major carbon source.PMID 33386486Read ↗

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