Article
Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole.
The EMBO journal - 1 Jul 1998
Lang T, Schaeffeler E, Bernreuther D, Bredschneider M, Wolf D H, Thumm M
Abstract excerpt
AUT2 and AUT7, two novel genes essential for autophagocytosis in the yeast Saccharomyces cerevisiae were isolated. AUT7 was identified as a low copy suppressor of autophagic defects in aut2-1 cells. Aut7p is a homologue of the rat microtubule-associated protein (MAP) light chain 3 (LC3). Aut2p an...
Topics
- Amino Acid Sequence
- Animals
- Autophagy
- Autophagy-Related Protein 8 Family
- Autophagy-Related Proteins
- Base Sequence
- Cysteine Endopeptidases
- DNA, Fungal
- Fungal Proteins
- Genes, Fungal
- Microtubule-Associated Proteins
- Molecular Sequence Data
- Open Reading Frames
- Phagosomes